1988•Journal of Clinical MicrobiologyOpen access

Rapid detection (4 h) of methicillin-resistant Staphylococcus aureus by a bioluminescence method

C H Park, Deborah L. Hixon, C M McLaughlin, James Francis Cook

Abstract

A 4-h bioluminescence method for methicillin susceptibility determination was compared with reference methods. Of the Staphylococcus aureus strains tested, 80 were methicillin resistant, 180 were methicillin susceptible, and 10 were borderline susceptible. There was 100% correlation between bioluminescence and reference methods for methicillin-susceptible and methicillin-resistant strains. All borderline-susceptible strains were identified as methicillin resistant by bioluminescence.

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Key concepts: Bioluminescence, Methicillin-resistant Staphylococcus aureus, Staphylococcus aureus, Microbiology, Micrococcaceae, Staphylococcal infections, Biology, Medicine