Candida catenulata Fungemia in a Cancer Patient
Mirjana Radosavljevic, H Koenig, Valérie Letscher‐Bru, Jocelyn Waller, Frédéric Maloisel, Bruno Lioure, Raoul Herbrecht
Abstract
Mirjana Radosavljevic, H Koenig, Valérie Letscher‐Bru, Jocelyn Waller, Frédéric Maloisel, Bruno Lioure, Raoul Herbrecht
Abstract
We report the first case of fungemia due to Candida catenulata, a contaminant of dairy products. C. catenulata was isolated from three blood cultures of a patient with gastric cancer. The patient failed to respond to fluconazole but recovered after treatment was switched to amphotericin B. In vitro, C. catenulata was susceptible to amphotericin B and itraconazole and was also susceptible to fluconazole in dose-dependent manner. The likely portal of entry was the digestive tract, as the patient often ate cheese and had multiple gastric ulcerations.
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We report the first case of fungemia due to Candida catenulata, a contaminant of dairy products. C. catenulata was isolated from three blood cultures of a patient with gastric cancer. The patient failed to respond to fluconazole but recovered after treatment was switched to amphotericin B. In vitro, C. catenulata was susceptible to amphotericin B and itraconazole and was also susceptible to fluconazole in dose-dependent manner. The likely portal of entry was the digestive tract, as the patient often ate cheese and had multiple gastric ulcerations.
Key concepts: Fungemia, Fluconazole, Amphotericin B, Itraconazole, Cancer, Mycosis, Medicine, Digestive tract