2011•Unpublished venueRequires access
Structural Studies of Retroviral Integrases
Mariusz Jaskólski, Jerry Alexandratos, Grzegorz Bujacz, Alexander Wlodawer
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Abstract
This chapter contains sections titled: Introduction Amino Acid Sequence and Domain Structure of Retroviral Integrases Crystallization of Integrase Catalytic Domain of Integrase N-Terminal Domain of Integrase C-Terminal Domain of Integrase Two-Domain Constructs Consisting of N and Cat Domains Two-Domain Constructs Consisting of Cat and C Domains Oligomeric States of Full-Length Integrase and Modeling of Its Structure Structural Studies of Inhibitor Complexes of Integrase Structural Basis of Enzymatic Activity of Integrase Concluding Remarks Acknowledgment References