Is There Iso-PT Symmetric Potential in Nature?

In recent years there are new interests on special symmetry in physical systems, called PT-symmetry with various ramifica-tions. Along with the isodual symmetry popularized by RM Santilli, these ideas form one of cornerstone in hadron physics. In the present article, we argue that it is plausible to generalise both ideas to become iso-PT symmetry which indicate there should be new potential obeying this symmetry. We also dis-cuss some possible interpretation of the imaginary solution of the solution of biquaternionic KGE (BQKGE); which indicate the plausible existence of the propose iso-PT symmetry. Further observation is of course recommended in order to refute or ver-ify this proposition.