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Pharmacological actions of Pongamia pinnata seeds--a preliminary study.

Ramesh Singh, Vinod Kumar Joshi, Richa Goel, Surendra S. Gambhir, Shankar Acharya

Abstract

Direct ethanolic and sequential petroleum ether, chloroform, acetone and ethanolic extracts (50-100 mg/kg, i.p.) of P. pinnata seeds given 30-60 min before revealed anti-inflammatory, analgesic and anti-ulcerogenic activities in rats. The activities were present maximum in petroleum ether and chloroform extracts. However, the extracts also showed shortening of pentobarbitone induced 'sleep time' in rats.

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Key concepts: Pongamia, Petroleum ether, Chloroform, Acetone, Traditional medicine, Chemistry, Ether, Analgesic