2009ARKIVOCOpen access

Synthesis of 2-ethynyl-4(3H)quinazolinone and 2-(1,3-butadienyl)-4(3H)quinazolinone

Jan Bergman, I. Romero

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Abstract

2-Ethynyl-4(3H)quinazolinone and 2-(1,3-butadienyl)-4(3H)quinazolinone have been synthesized by cyclizations from appropriate precursors.These two molecules are of interest as analogues of the known p-53 reactivator 2-vinyl-4(3H)quinazolinone.

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2-Ethynyl-4(3H)quinazolinone and 2-(1,3-butadienyl)-4(3H)quinazolinone have been synthesized by cyclizations from appropriate precursors.These two molecules are of interest as analogues of the known p-53 reactivator 2-vinyl-4(3H)quinazolinone.

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Available abstract

2-Ethynyl-4(3H)quinazolinone and 2-(1,3-butadienyl)-4(3H)quinazolinone have been synthesized by cyclizations from appropriate precursors.These two molecules are of interest as analogues of the known p-53 reactivator 2-vinyl-4(3H)quinazolinone.

Key concepts: Quinazolinone, Chemistry, Molecule, Stereochemistry, Combinatorial chemistry, Organic chemistry

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Synthesis of 2-ethynyl-4(3H)quinazolinone and 2-(1,3-butadienyl)-4(3H)quinazolinone — Research Paper | ScholarLens