2011•Methods and principles in medicinal chemistryRequires access
Neuraminidase Inhibitors as Anti‐Influenza Agents
Willard Lew, Michael Z. Wang, Xiaowu Chen, James F. Rooney, Choung Kim
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Abstract
This chapter contains sections titled: Introduction Influenza Neuraminidase as a Drug Target Neuraminidase Active Site and Inhibitor Binding Small-Molecule Inhibitors of Influenza Neuraminidase Mechanism of Resistance Influenza Neuraminidase Inhibitors Based on Other Scaffolds Clinical Use of Neuraminidase Inhibitors Concluding Remarks References