1979•Journal of BacteriologyOpen access

Decreased binding of polymyxin by polymyxin-resistant mutants of Salmonella typhimurium

Martti Vaara, Timo Vaara, Matti Sarvas

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Abstract

Polymyxin-resistant pmrA strains were shown to absorb only about 25% of the amount of polymyxin absorbed by the corresponding polymyxin-sensitive parent strains. The lipopolysaccharide from the pmrA strains bound less polymyxin than the lipopolysaccharide from the parent strains.

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Polymyxin-resistant pmrA strains were shown to absorb only about 25% of the amount of polymyxin absorbed by the corresponding polymyxin-sensitive parent strains. The lipopolysaccharide from the pmrA strains bound less polymyxin than the lipopolysaccharide from the parent strains.

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Available abstract

Polymyxin-resistant pmrA strains were shown to absorb only about 25% of the amount of polymyxin absorbed by the corresponding polymyxin-sensitive parent strains. The lipopolysaccharide from the pmrA strains bound less polymyxin than the lipopolysaccharide from the parent strains.

Key concepts: Polymyxin, Polymyxin B, Biology, Microbiology, Lipopolysaccharide, Salmonella, Mutant, Bacteria

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