Decreased binding of polymyxin by polymyxin-resistant mutants of Salmonella typhimurium
Martti Vaara, Timo Vaara, Matti Sarvas
Abstract
Martti Vaara, Timo Vaara, Matti Sarvas
Abstract
Polymyxin-resistant pmrA strains were shown to absorb only about 25% of the amount of polymyxin absorbed by the corresponding polymyxin-sensitive parent strains. The lipopolysaccharide from the pmrA strains bound less polymyxin than the lipopolysaccharide from the parent strains.
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Polymyxin-resistant pmrA strains were shown to absorb only about 25% of the amount of polymyxin absorbed by the corresponding polymyxin-sensitive parent strains. The lipopolysaccharide from the pmrA strains bound less polymyxin than the lipopolysaccharide from the parent strains.
Key concepts: Polymyxin, Polymyxin B, Biology, Microbiology, Lipopolysaccharide, Salmonella, Mutant, Bacteria