2006•Dermatology Online JournalRequires access

Three cases of toxic skin eruptions due to methotrexate and a compilation of methotrexate induced skin eruptions

Noah Scheinfeld

Abstract

Methotrexate is an antimetabolite used as a treatment for a variety of neoplastic and inflammatory diseases. It has a variety of cutaneous side effects, in particular when administered in high doses. This is a report of cutaneous eruptions in three patients treated with methotrexate and a review of eruptions linked to methotrexate.

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Key concepts: Methotrexate, Antimetabolite, Medicine, Dermatology, Antifolate, Internal medicine