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Comparative Human Genomics

I. King Jordan, Eugene V. Koonin

Abstract

Abstract Comparative genomics involves the comparison of features of completely sequenced (or nearly so) genomes. Comparative sequence analyses facilitate both the functional annotation of genomes and whole‐genome approaches to evolutionary issues. We present a review of the field of comparative genomics and point out how the comparative approach can be used to help better understand the human genome sequence.

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Key concepts: Comparative genomics, Genomics, Genome, Human genome, Annotation, Computational biology, Sequence (biology), Personal genomics