2006•Encyclopedia of Life SciencesRequires access

Relatives‐based Test for Linkage Disequilibrium: The Transmission/Disequilibrium Test (TDT)

Richard S. Spielman, Warren J. Ewens

Abstract

Abstract Genes that contribute to complex genetic diseases can sometimes be identified by studies that show genetic linkage, or association, with marker genes. The transmission/disequilibrium test is a procedure that tests for the simultaneous presence of these two genetic phenomena.

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Available abstract

Key concepts: Disequilibrium, Linkage disequilibrium, Transmission disequilibrium test, Genetics, Linkage (software), Biology, Genetic association, Test (biology)