2007Turkiye Klinikleri Tip Bilimleri DergisiRequires access

Dislipidemili Hastalarda Subklinik Hipotiroidi Sikliği

Hacer Şen, Ömer Dönderici, Onur Cengiz, Sercan Cansaran, İbrahim Türker

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Abstract

Objective: It is well-established that dyslypidemia occurs in clinical hypotyhroidism. However, data on subclinical hypothyroidism is controversial and are limited to total cholester ol. In this study, we aimed to determine the prevalence of subclinical hypothyroidism in all subgroups of dyslipidemia. Material and Methods: The study group consisted of 356 patients (277 females, 79 males) who presented to the internal me dicine outpatient clinic. Thus, we examined the lipid profile a nd thyroid function tests in all patients. Then, for all groups wi th or without dyslipidemia, we examined the prevalence of subclinical hypothyroidism and compared the groups for statistical sig nificance. Results: The frequency of subclinical hypothyroid ism was 5.9% in cases with hypercholesterolemia and 6.6% in those without, 4.7% in patients with high levels of LDL-cholesterol and in 7.2% in those with normal levels, in 7.4% of hypertriglyce ridemia patients and in 5.0% in those without and in 2.6% cas es with low levels of HDL-cholesterol level and in 7.1% in those with normal levels. According to these results, there was no st atistically significant difference between patients with and witho ut dyslipidemia. Similarly, there was no significant difference between subclinical hypotyhroid patients and the eutyhroid one s. Conclusion: Based on these results, we suggest that subclinical hypothyroidism is similar to euthyroidism with regard t o dyslipidemia.

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Objective: It is well-established that dyslypidemia occurs in clinical hypotyhroidism. However, data on subclinical hypothyroidism is controversial and are limited to total cholester ol. In this study, we aimed to determine the prevalence of subclinical hypothyroidism in all subgroups of dyslipidemia. Material and Methods: The study group consisted of 356 patients (277 females, 79 males) who presented to the internal me dicine outpatient clinic. Thus, we examined the lipid profile a nd thyroid function tests in all patients. Then, for all groups wi th or without dyslipidemia, we examined the prevalence of subclinical hypothyroidism and compared the groups for statistical sig nificance. Results: The frequency of subclinical hypothyroid ism was 5.9% in cases with hypercholesterolemia and 6.6% in those without, 4.7% in patients with high levels of LDL-cholesterol and in 7.2% in those with normal levels, in 7.4% of hypertriglyce ridemia patients and in 5.0% in those without and in 2.6% cas es with low levels of HDL-cholesterol level and in 7.1% in those with normal levels. According to these results, there was no st atistically significant difference between patients with and witho ut dyslipidemia. Similarly, there was no significant difference between subclinical hypotyhroid patients and the eutyhroid one s. Conclusion: Based on these results, we suggest that subclinical hypothyroidism is similar to euthyroidism with regard t o dyslipidemia.

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Available abstract

Objective: It is well-established that dyslypidemia occurs in clinical hypotyhroidism. However, data on subclinical hypothyroidism is controversial and are limited to total cholester ol. In this study, we aimed to determine the prevalence of subclinical hypothyroidism in all subgroups of dyslipidemia. Material and Methods: The study group consisted of 356 patients (277 females, 79 males) who presented to the internal me dicine outpatient clinic. Thus, we examined the lipid profile a nd thyroid function tests in all patients. Then, for all groups wi th or without dyslipidemia, we examined the prevalence of subclinical hypothyroidism and compared the groups for statistical sig nificance. Results: The frequency of subclinical hypothyroid ism was 5.9% in cases with hypercholesterolemia and 6.6% in those without, 4.7% in patients with high levels of LDL-cholesterol and in 7.2% in those with normal levels, in 7.4% of hypertriglyce ridemia patients and in 5.0% in those without and in 2.6% cas es with low levels of HDL-cholesterol level and in 7.1% in those with normal levels. According to these results, there was no st atistically significant difference between patients with and witho ut dyslipidemia. Similarly, there was no significant difference between subclinical hypotyhroid patients and the eutyhroid one s. Conclusion: Based on these results, we suggest that subclinical hypothyroidism is similar to euthyroidism with regard t o dyslipidemia.

Key concepts: Dyslipidemia, Subclinical infection, Medicine, Internal medicine, Significant difference, Gastroenterology, Lipid profile, Cholesterol

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