1981The Journal of ImmunologyRequires access

Unusual phenotypes of human inducer T cells as measured by OKT4 and related monoclonal antibodies.

Mark A. Bach, Françoise Phan-Dinh-Tuy, Jean‐François Bach, Donald F. H. Wallach, William E. Biddison, S O Sharrow, Gideon Goldstein, Patrick C. Kung

Open publisher page 81 citations

Abstract

OKT4, a murine monoclonal antibody, was previously shown to react with inducer/helper T cells in man. We now report the absence of this reactivity in 2 subjects of African ancestry and the production of 4 new monoclonal antibodies (OKT4A-D) that detect distinct antigens on human inducer/helper T cells.

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What this paper is about

OKT4, a murine monoclonal antibody, was previously shown to react with inducer/helper T cells in man. We now report the absence of this reactivity in 2 subjects of African ancestry and the production of 4 new monoclonal antibodies (OKT4A-D) that detect distinct antigens on human inducer/helper T cells.

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OpenAlex reports 81 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

OKT4, a murine monoclonal antibody, was previously shown to react with inducer/helper T cells in man. We now report the absence of this reactivity in 2 subjects of African ancestry and the production of 4 new monoclonal antibodies (OKT4A-D) that detect distinct antigens on human inducer/helper T cells.

Key concepts: Monoclonal antibody, Inducer, Antibody, Antigen, Phenotype, Monoclonal, Molecular biology, Biology

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Unusual phenotypes of human inducer T cells as measured by OKT4 and related monoclonal antibodies. — Research Paper | ScholarLens