Changes in Blood Metabolites, Endoerines and Milk Yield of Crossbred Cows Treated with Recombinant Bovine Somatotropin

Mishra, A., Mahapatra, R.K. and Shukla, D.C. 2006. Changes in blood metabolites, endoerines and milk yield of crossbred cows treated with recombinant bovine somatotropin. J. Appl. Anim. Res., 30: 33–36. In order to investigate the effect of recombinant bovine somatotropin (rbST; Boostin-250) on blood metabolites, certain endoerines and milk yield oflactating crossbred cows, 30 lactating cows were divided into 2 groups as control (n=10) and experimental (n=20). Experimental animals were injected 250 mg of rbST on 0, 14 and 28 day subcutaneously at ischiorectal fosse and control animals were given placebo of 2 ml normal saline. Blood metabolites (glucose, BUN, triglycerides, total proteins, albumin, globulin, sodium and potassium) and hormones T4 and insulin were not altered by rbST injection. Serum growth hormone (GH) increased significantly (P<0.001) due to rbST injection but not milk GH. However, there was a significant (P<O.001) decrease in T3 level in rbST treated group over control group. The weekly average milk yield showed a significant (P<0.001) increase of 33% in rbST treated group over the control group. It is concluded that 250 mg rbST can be used for short duration to increase the milk yield of crossbred cows.