Alison C. Lloyd
Abstract
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The Ras/Raf/MEK/ERK signaling pathway is one of the best understood signal routes in cells. Recent studies add complexity to this cascade by indicating that the two ERK kinases, ERK1 (p44ERK1) and ERK2 (p42ERK2), may have distinct functions.
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The Ras/Raf/MEK/ERK signaling pathway is one of the best understood signal routes in cells. Recent studies add complexity to this cascade by indicating that the two ERK kinases, ERK1 (p44ERK1) and ERK2 (p42ERK2), may have distinct functions.
Key concepts: MAPK/ERK pathway, Extracellular signal-regulated kinases, Kinase, Cell biology, Mitogen-activated protein kinase, Signal transduction, Biology, Computational biology