Cytochalasin B-sensitive 2-Deoxy-d-glucose Transport in Adipose Cell Ghosts
Michael Czech, David G. Lynn, William S. Lynn
Abstract
Michael Czech, David G. Lynn, William S. Lynn
Abstract
Glucose oxidation of isolated white fat cells in the presence or absence of insulin was abolished by as little as 3 pM cytochalasin B in medium containing 0.2 mM glucose.This agent inhibited fat cell D-Il-Wlglucose conversion to COa half-maximally at 0.2 pM, which was about 700 and 30 times as effective as phlorizin and phloretin, respectively.
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Glucose oxidation of isolated white fat cells in the presence or absence of insulin was abolished by as little as 3 pM cytochalasin B in medium containing 0.2 mM glucose.This agent inhibited fat cell D-Il-Wlglucose conversion to COa half-maximally at 0.2 pM, which was about 700 and 30 times as effective as phlorizin and phloretin, respectively.
Key concepts: Phloretin, Phlorizin, Cytochalasin B, Adipose tissue, Glucose transporter, Chemistry, White adipose tissue, Cell