2015European Journal of DermatologyRequires access

Treatment of a patient with neutrophilic dermatoses with granulocyte and monocyte adsorption apheresis: effects on serum cytokine levels

Koji Kamiya, Yumi Aoyama, Mariko Kawata, Tetsuya Takiguchi, Seiko Mitsui, Y. Tokura, Keiji Iwatsuki

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Abstract

Neutrophilic dermatoses are a group of skin disorders characterized by intense epidermal and/or dermal inflammatory infiltrates composed of neutrophils with no evidence of infection [1]. They are often associated with ulcerative colitis and Crohn's disease [2, 3].Granulocyte and monocyte adsorptive apheresis (GMA) is an extracorporeal circulation therapy that effectively removes activated granulocytes and monocytes from peripheral blood to correct imbalances in immunological regulatory mechanisms. [...]

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Neutrophilic dermatoses are a group of skin disorders characterized by intense epidermal and/or dermal inflammatory infiltrates composed of neutrophils with no evidence of infection [1]. They are often associated with ulcerative colitis and Crohn's disease [2, 3].Granulocyte and monocyte adsorptive apheresis (GMA) is an extracorporeal circulation therapy that effectively removes activated granulocytes and monocytes from peripheral blood to correct imbalances in immunological regulatory mechanisms. [...]

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Available abstract

Neutrophilic dermatoses are a group of skin disorders characterized by intense epidermal and/or dermal inflammatory infiltrates composed of neutrophils with no evidence of infection [1]. They are often associated with ulcerative colitis and Crohn's disease [2, 3].Granulocyte and monocyte adsorptive apheresis (GMA) is an extracorporeal circulation therapy that effectively removes activated granulocytes and monocytes from peripheral blood to correct imbalances in immunological regulatory mechanisms. [...]

Key concepts: Apheresis, Medicine, Granulocyte, Monocyte, Immunology, Cytokine, Leukapheresis, Pyoderma gangrenosum

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Treatment of a patient with neutrophilic dermatoses with granulocyte and monocyte adsorption apheresis: effects on serum cytokine levels — Research Paper | ScholarLens