Treatment of a patient with neutrophilic dermatoses with granulocyte and monocyte adsorption apheresis: effects on serum cytokine levels
Koji Kamiya, Yumi Aoyama, Mariko Kawata, Tetsuya Takiguchi, Seiko Mitsui, Y. Tokura, Keiji Iwatsuki
Abstract
Koji Kamiya, Yumi Aoyama, Mariko Kawata, Tetsuya Takiguchi, Seiko Mitsui, Y. Tokura, Keiji Iwatsuki
Abstract
Neutrophilic dermatoses are a group of skin disorders characterized by intense epidermal and/or dermal inflammatory infiltrates composed of neutrophils with no evidence of infection [1]. They are often associated with ulcerative colitis and Crohn's disease [2, 3].Granulocyte and monocyte adsorptive apheresis (GMA) is an extracorporeal circulation therapy that effectively removes activated granulocytes and monocytes from peripheral blood to correct imbalances in immunological regulatory mechanisms. [...]
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Neutrophilic dermatoses are a group of skin disorders characterized by intense epidermal and/or dermal inflammatory infiltrates composed of neutrophils with no evidence of infection [1]. They are often associated with ulcerative colitis and Crohn's disease [2, 3].Granulocyte and monocyte adsorptive apheresis (GMA) is an extracorporeal circulation therapy that effectively removes activated granulocytes and monocytes from peripheral blood to correct imbalances in immunological regulatory mechanisms. [...]
Key concepts: Apheresis, Medicine, Granulocyte, Monocyte, Immunology, Cytokine, Leukapheresis, Pyoderma gangrenosum