Obesity and Diabetes: Lipotoxicity

This chapter contains sections titled: Introduction White Adipose Tissue at the Center of Lipid Homeostasis and Delivery Insulin Resistance in Adipocytes Disrupts the Balance between Lipid Storage and Secretion Scenarios that may Result in Ectopic Fat Deposition Mechanisms Contributing to the Lipotoxicity in the Peripheral Organs Impaired Oxidation as a Trigger for Lipotoxicity Pancreatic β-Cell as a Target for Lipotoxicity New Analytical and Computational Methods to Identify Lipotoxicity-Related Metabolic Networks Lessons from Lipotoxicity – Potential Antilipotoxic Therapeutic Strategies References