2008Unpublished venueRequires access

Measles as an Oncolytic Virus

Adele K. Fielding

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Abstract

This chapter contains sections titled: Introduction Measles virus and the consequences of natural infection MV vaccine MV genetics and engineering MV receptors Animal models for the study of MV pathogenesis and oncolysis Oncolytic activity of MV Mechanism of specificity Targeting MV entry Enhancing the oncolytic activity of MV Interactions with the immune system Potential specific toxicities of clinical use of replicating attenuated MV Clinical trials Conclusions References

About this research paper

What this paper is about

This chapter contains sections titled: Introduction Measles virus and the consequences of natural infection MV vaccine MV genetics and engineering MV receptors Animal models for the study of MV pathogenesis and oncolysis Oncolytic activity of MV Mechanism of specificity Targeting MV entry Enhancing the oncolytic activity of MV Interactions with the immune system Potential specific toxicities of clinical use of replicating attenuated MV Clinical trials Conclusions References

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Method / approach

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Available abstract

This chapter contains sections titled: Introduction Measles virus and the consequences of natural infection MV vaccine MV genetics and engineering MV receptors Animal models for the study of MV pathogenesis and oncolysis Oncolytic activity of MV Mechanism of specificity Targeting MV entry Enhancing the oncolytic activity of MV Interactions with the immune system Potential specific toxicities of clinical use of replicating attenuated MV Clinical trials Conclusions References

Key concepts: Oncolytic virus, Measles virus, Virology, Measles, Virus, Measles vaccine, Immune system, Clinical trial

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