Physiological Role of Na,K‐ATPase Isoforms
Jerry B. Lingrel, Jonathan Neumann, Iva Dostanic, Amy E. Moseley
Abstract
Jerry B. Lingrel, Jonathan Neumann, Iva Dostanic, Amy E. Moseley
Abstract
This chapter contains sections titled: Introduction α Isoforms β Isoforms Physiological Role of Na,K-ATPase Isoforms Duplication and Divergence of α and β Isoform Genes Enzymatic Properties of α and β Isoform Genes Differential Expression of α and β Isoform Genes Non-transport Function of the Na,K-ATPase In Vivo Studies of Differential Isoform Function Gene Knock-out of the β2 Isoform Gene Replacement of the β2 Isoform with β1 Overexpression of the α2 Isoform Gene Knock-out of the α1 and α2 Isoform Genes Model for Differential Function of the α1 Isoform and the α2, α3 and α4 Isoforms Na,K-ATPase Isoforms and Disease Migraine Headache and the α2 Isoform Acknowledgments References
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This chapter contains sections titled: Introduction α Isoforms β Isoforms Physiological Role of Na,K-ATPase Isoforms Duplication and Divergence of α and β Isoform Genes Enzymatic Properties of α and β Isoform Genes Differential Expression of α and β Isoform Genes Non-transport Function of the Na,K-ATPase In Vivo Studies of Differential Isoform Function Gene Knock-out of the β2 Isoform Gene Replacement of the β2 Isoform with β1 Overexpression of the α2 Isoform Gene Knock-out of the α1 and α2 Isoform Genes Model for Differential Function of the α1 Isoform and the α2, α3 and α4 Isoforms Na,K-ATPase Isoforms and Disease Migraine Headache and the α2 Isoform Acknowledgments References
Key concepts: Gene isoform, Gene, Biology, Isozyme, ATPase, Function (biology), Gene duplication, Molecular biology