2005Unpublished venueRequires access

The SCF Ubiquitin E3 Ligase

Leigh Ann Higa, Hui Zhang

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Abstract

This chapter contains sections titled: Introduction Discovery of the SCF Complex The Components of the SCF Complex Roc1/Rbx1/Hrt1 Cullin-1 (Cul1) Skp1 F-box Proteins E2-conjugating Enzymes for the SCF E3 Ligases Substrates and Substrate Recognition Skp2 and Its Substrates β-Trcp and Its Substrates Yeast Cdc4 and Its Substrates Structure of the SCF E3 Ligase Complex Regulation of SCF Activity The SCF Complex and the Related Cullin-containing Ubiquitin E3 Ligase Perspectives

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What this paper is about

This chapter contains sections titled: Introduction Discovery of the SCF Complex The Components of the SCF Complex Roc1/Rbx1/Hrt1 Cullin-1 (Cul1) Skp1 F-box Proteins E2-conjugating Enzymes for the SCF E3 Ligases Substrates and Substrate Recognition Skp2 and Its Substrates β-Trcp and Its Substrates Yeast Cdc4 and Its Substrates Structure of the SCF E3 Ligase Complex Regulation of SCF Activity The SCF Complex and the Related Cullin-containing Ubiquitin E3 Ligase Perspectives

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Available abstract

This chapter contains sections titled: Introduction Discovery of the SCF Complex The Components of the SCF Complex Roc1/Rbx1/Hrt1 Cullin-1 (Cul1) Skp1 F-box Proteins E2-conjugating Enzymes for the SCF E3 Ligases Substrates and Substrate Recognition Skp2 and Its Substrates β-Trcp and Its Substrates Yeast Cdc4 and Its Substrates Structure of the SCF E3 Ligase Complex Regulation of SCF Activity The SCF Complex and the Related Cullin-containing Ubiquitin E3 Ligase Perspectives

Key concepts: Cullin, Skp1, Cell division control protein 4, Ubiquitin ligase, DNA ligase, Ubiquitin, SKP2, F-box protein

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