1998•PubMedOpen access

[Analysis of the reactive capacity of intracerebral circulation with CO2. A method easily performed].

A Baptista, J Ribeiro

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Abstract

Maintenance of cerebral perfusion pressure is a prerequisite for the prevention of cerebral ischaemia. Physiological fluctuations in systemic perfusion pressure are compensated by cerebrovascular autoregulation. Cerebral perfusion reserve may be determined by assessing changes in cerebral blood flow using vasodilating stimuli. Transcranial Doppler has been used to assess cerebral blood flow speed in response to those stimuli. We describe a method using Transcranial Doppler with CO2 to analyse cerebral vasoreactivity. The method can be useful to determine hemodynamic reserve in different cerebral ischaemic diseases.

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Maintenance of cerebral perfusion pressure is a prerequisite for the prevention of cerebral ischaemia. Physiological fluctuations in systemic perfusion pressure are compensated by cerebrovascular autoregulation. Cerebral perfusion reserve may be determined by assessing changes in cerebral blood flow using vasodilating stimuli. Transcranial Doppler has been used to assess cerebral blood flow speed in response to those stimuli. We describe a method using Transcranial Doppler with CO2 to analyse cerebral vasoreactivity. The method can be useful to determine hemodynamic reserve in different cerebral ischaemic diseases.

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Available abstract

Maintenance of cerebral perfusion pressure is a prerequisite for the prevention of cerebral ischaemia. Physiological fluctuations in systemic perfusion pressure are compensated by cerebrovascular autoregulation. Cerebral perfusion reserve may be determined by assessing changes in cerebral blood flow using vasodilating stimuli. Transcranial Doppler has been used to assess cerebral blood flow speed in response to those stimuli. We describe a method using Transcranial Doppler with CO2 to analyse cerebral vasoreactivity. The method can be useful to determine hemodynamic reserve in different cerebral ischaemic diseases.

Key concepts: Cerebral blood flow, Cerebral perfusion pressure, Autoregulation, Cerebral autoregulation, Transcranial Doppler, Cerebral circulation, Medicine, Perfusion

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[Analysis of the reactive capacity of intracerebral circulation with CO2. A method easily performed]. — Research Paper | ScholarLens