2009•Zhongguo weishengtaixue zazhiRequires access
Effect of attaining upon the imbalance of intestinal flora induced by antibiotics and immune function in rats.
Zhang HaiQiang, Xin Hao Yang, Lv YinWen, Haixia Zhang, Juanjuan Zhang, Cui Yun-long
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Abstract
Objective To investigate the effect of Ataining upon the imbalance of intestinal flora induced by antibiotics and immune function in rats.Method Dysbacteriosis models were induced by antibiotics and then given Ataining treatment,followed by intestinal flora analysis,delayed type hypersensitivity test,NK cell activity assay,and T lymphocyte transformation rate determination.Result The balance of intestinal flora was destroyed in the antibiotics group.The NK cell activity in the antibiotics group was decreased signifigantly than that of the normal group(P0.01).After Ataining treatment,the balance of intestinal flora was restored.In the delayed type hypersensitivity tests,the foot thickening of Ataining group was significantly higher than that of normal group and the antibiotics group(P0.05),and its T lymphoid cell conversion rate was increased significantly than that of normal and model groups(P0.01).Conclusion Ataining could restore the balance of intestinal flora effectively and improve the immune function.