2001•PubMedRequires access

[About side effects of platinum drugs].

Katarzyna Waszkiewicz

Abstract

The work presents current view about toxic effects of platinum anticancer drugs. In the first part, the toxic effects of cisplatin as nephrotoxicity, ototoxicity, myelosuppression, anaphylactic-like reactions, neurotoxicity and gastrotoxicity are presented. The second part describes mechanisms of nephrotoxicity of cisplatin. In the third part, the toxicity of carboplatin and iproplatin are reviewed.

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Available abstract

Key concepts: Ototoxicity, Carboplatin, Nephrotoxicity, Cisplatin, Toxicity, Neurotoxicity, Pharmacology, Medicine