1987•Journal of VirologyOpen access

Wild-type bacteriophage T4 is restricted by the lambda rex genes

Sidney T. Shinedling, David H Parma, Larry Gold

Abstract

The bacteriophage T4 rII genes and the lambda rex (r exclusion) genes interact; rII mutants are unable to productively infect rex+ lambda lysogens. The relationship between rex and rII has been found to be quantitative, and plasmid clones of rex have excluded not only rII mutants but T4 wild type and most other bacteriophages as well. Mutations in the T4 motA gene substantially reversed exclusion of T4 by rex.

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Key concepts: Lysogen, Biology, Bacteriophage, Lysogenic cycle, Gene, Mutant, Genetics, Lambda