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HEMOLYTIC DISEASE OF THE NEWBORN DUE TO ABO INCOMPATIBILITY: A STUDY OF THE USE OF GROUP O ERYTHROCYTES IN AB PLASMA

Donald L. Goldfarb, Victor Ginsberg, Mary Kaufman, Margaret G. Robinson, R. Janet Watson

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Abstract

Twenty-four infants with hemolytic disease of the newborn due to ABO incompatibility requiring exchange transfusion were treated randomly with either group O blood low in titer for iso-antibodies or washed packed group O erythrocytes resuspended in group AB plasma. No significant differences in survival, sequelae, number of exchange transfusions required or the course of postexchange bilirubin levels was observed. It is concluded that group O cells in AB plasma is not an improvement over conventional group O blood.

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Twenty-four infants with hemolytic disease of the newborn due to ABO incompatibility requiring exchange transfusion were treated randomly with either group O blood low in titer for iso-antibodies or washed packed group O erythrocytes resuspended in group AB plasma. No significant differences in survival, sequelae, number of exchange transfusions required or the course of postexchange bilirubin levels was observed. It is concluded that group O cells in AB plasma is not an improvement over conventional group O blood.

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Available abstract

Twenty-four infants with hemolytic disease of the newborn due to ABO incompatibility requiring exchange transfusion were treated randomly with either group O blood low in titer for iso-antibodies or washed packed group O erythrocytes resuspended in group AB plasma. No significant differences in survival, sequelae, number of exchange transfusions required or the course of postexchange bilirubin levels was observed. It is concluded that group O cells in AB plasma is not an improvement over conventional group O blood.

Key concepts: ABO blood group system, Medicine, Hemolytic disease of the newborn (ABO), Antibody, Blood type (non-human), Titer, Group A, Bilirubin

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HEMOLYTIC DISEASE OF THE NEWBORN DUE TO ABO INCOMPATIBILITY: A STUDY OF THE USE OF GROUP O ERYTHROCYTES IN AB PLASMA — Research Paper | ScholarLens