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A proliferation-associated rat cell surface antigen recognized by a murine monoclonal antibody.

Yosuke Hashimoto, Takashi Masuko, Hideo Yagita∥, N. Endo, Jun Kanazawa, Junichi Tazawa

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Abstract

B3 murine IgG1 monoclonal antibody against BC47 rat bladder cancer detected an antigen distributed on the cell surface of neoplastic cells and proliferating normal tissue cells. The percentage of B3 antigen-positive cells in lymphocytes was increased by mitogen stimulation. The molecular weight of the antigen was 130,000 or 140,000 daltons.

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B3 murine IgG1 monoclonal antibody against BC47 rat bladder cancer detected an antigen distributed on the cell surface of neoplastic cells and proliferating normal tissue cells. The percentage of B3 antigen-positive cells in lymphocytes was increased by mitogen stimulation. The molecular weight of the antigen was 130,000 or 140,000 daltons.

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Available abstract

B3 murine IgG1 monoclonal antibody against BC47 rat bladder cancer detected an antigen distributed on the cell surface of neoplastic cells and proliferating normal tissue cells. The percentage of B3 antigen-positive cells in lymphocytes was increased by mitogen stimulation. The molecular weight of the antigen was 130,000 or 140,000 daltons.

Key concepts: Monoclonal antibody, Antigen, Antibody, Molecular biology, Cell, Monoclonal, Biology, Immunology

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