뉴질랜드 흰 토끼의 각막 두께, 내피세포 및 안압에 관한 조사
장화석, 이대엽, 강은희, 이재훈, 조양경, 김만수, 김휘율
Abstract
장화석, 이대엽, 강은희, 이재훈, 조양경, 김만수, 김휘율
Abstract
Rabbit’s cornea is the most common thing that used for researches in ophthalmology, so many experimentations have done. The purpose of this study was to survey the corneal pachymetry, tonometry and specular microscopy in New Zealand white rabbits. Three months old male rabbits (2.9 ± 0.2 ㎏) were examined with contact the specular microscope to evaluate the endothelial cell density, coefficiency of variation and the percentage of hexagonal cells in the central cornea. For the pachymetry, ultrasonic pachymeter was used for central cornea in each twenty rabbits, and tonometry was performed forty rabbit’s eyes to evaluate the intraocular pressure. Corneal endothelial cell density in New Zealand white rabbit was 3304 ± 354 cell/㎟. Coefficiency of variation was 45.8 ± 2 and the percentage of hexagonal cells in the central cornea was 44.4 ± 11%. The pachymetry of cornea was 346.1 ± 21 ㎛ and tonometry of eye was 14.3 ± 2 ㎜Hg. It is considered that normal New Zealand white rabbit’s pachymetry, specular microscopy and tonometry were useful basic data of rabbit’s cornea for research and clinic in veterinary ophthalmology.
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Rabbit’s cornea is the most common thing that used for researches in ophthalmology, so many experimentations have done. The purpose of this study was to survey the corneal pachymetry, tonometry and specular microscopy in New Zealand white rabbits. Three months old male rabbits (2.9 ± 0.2 ㎏) were examined with contact the specular microscope to evaluate the endothelial cell density, coefficiency of variation and the percentage of hexagonal cells in the central cornea. For the pachymetry, ultrasonic pachymeter was used for central cornea in each twenty rabbits, and tonometry was performed forty rabbit’s eyes to evaluate the intraocular pressure. Corneal endothelial cell density in New Zealand white rabbit was 3304 ± 354 cell/㎟. Coefficiency of variation was 45.8 ± 2 and the percentage of hexagonal cells in the central cornea was 44.4 ± 11%. The pachymetry of cornea was 346.1 ± 21 ㎛ and tonometry of eye was 14.3 ± 2 ㎜Hg. It is considered that normal New Zealand white rabbit’s pachymetry, specular microscopy and tonometry were useful basic data of rabbit’s cornea for research and clinic in veterinary ophthalmology.
Key concepts: Cornea, Ophthalmology, Intraocular pressure, Medicine, Hexagonal crystal system, Corneal pachymetry, Rabbit (cipher), Optometry