2000•Nature ImmunologyRequires access

Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule

Nils Holler, Rossana Zaru, Olivier Micheau, Margot Thome, Antoine Attinger, Salvatore Valitutti, Jean-Luc Bodmer, Pascal Schneider, Brian Seed, Jürg Tschopp

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Key concepts: FADD, Death domain, Cell biology, Programmed cell death, Fas ligand, Apoptosis, Caspase, Caspase 8

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Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule — Research Paper | ScholarLens