1995•Unpublished venueRequires access

Myeloma : biology and management

J. S. Malpas, Daniel E. Bergsagel, Robert A. Kyle

Abstract

Part 1 - Pathophysiology. Immunoglobulins. Antibody-secreting cells and their origins. Molecular biology of multiple myeloma. Cytokines and cytokine receptors in human multiple myeloma. Bone marrow biopsy and aspiration for diagnosis of multiple myeloma. The role of cytogenetics in myeloma. Multiple myeloma: A brief history. Part 2 - Clinical features. Epidemiology of myeloma. Clinical presentation and diagnosis. Laboratory investigation of myeloma. Radiology features of myeloma. [Prognostic factor in multiple myeloma - might be deleted]. Part 3 - Therapy of myeloma. Chemotherapy of myeloma. Radiotherapy of myeloma. Haematopoitic stem cell transplantation in multiple myeloma. Management of haematologic complications of myeloma. Disorders of calcium and skeletal metabolism. Management of renal complications. Neurological manifestations of myeloma and their management. Infections in myeloma. Psychosocial aspects of multiple myeloma. Myeloma: Patient and family perspectives. Part 4 - Other disorders associated with paraproteinaemia. Monoclonal gammopathies of undetermined significance. Amyloidosis. Heavy-chain diseases. Waldenstrom's macroglobulinaemia

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Available abstract

Key concepts: Multiple myeloma, Medicine, Myeloma protein, Bone marrow, Pathology, Oncology, Immunology