Concentration and Time Dependent Growth Inhibition and Metabolism in vitro by 2’,2’-Difluoro-Deoxycytidine (Gemcitabine)
Veronique W.T. Ruiz van Haperen, Gijsbert Veerman, Paul Noordhuis, Jan B. Vermorken, Godefridus J. Peters
Abstract
Veronique W.T. Ruiz van Haperen, Gijsbert Veerman, Paul Noordhuis, Jan B. Vermorken, Godefridus J. Peters
Abstract
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Key concepts: Deoxycytidine kinase, Deoxycytidine, Gemcitabine, Deamination, Chemistry, Cytidine deaminase, Cancer research, Ribonucleotide reductase