Butyrylcholinesterase: Overview, Structure, and Function
Oksana Lockridge, Ellen G. Duysen, Patrick Masson
Abstract
Oksana Lockridge, Ellen G. Duysen, Patrick Masson
Abstract
This chapter contains sections titled: Introduction Name History Why was Butyrylcholinesterase Rather than Acetylcholinesterase Chosen as a Therapeutic? Function of Butyrylcholinesterase Deduced from Studies In People Function of Butyrylcholinesterase Deduced from the Knockout Mouse Function of Butyrylcholinesterase Deduced from the G117H Transgenic Mouse Function of Butyrylcholinesterase Deduced from the AChE Knockout Mouse Function of Butyrylcholinesterase Deduced from Tissue-Specific Deletions of Acetylcholinesterase and Anchor Proteins Function of Butyrylcholinesterase Deduced from Protection Experiments with Purified Butyrylcholinesterase Butyrylcholinesterase in Human Tissues Summary: Functions of Butyrylcholinesterase Structure of Human Butyrylcholinesterase Conclusions and Future Directions Acknowledgments References
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This chapter contains sections titled: Introduction Name History Why was Butyrylcholinesterase Rather than Acetylcholinesterase Chosen as a Therapeutic? Function of Butyrylcholinesterase Deduced from Studies In People Function of Butyrylcholinesterase Deduced from the Knockout Mouse Function of Butyrylcholinesterase Deduced from the G117H Transgenic Mouse Function of Butyrylcholinesterase Deduced from the AChE Knockout Mouse Function of Butyrylcholinesterase Deduced from Tissue-Specific Deletions of Acetylcholinesterase and Anchor Proteins Function of Butyrylcholinesterase Deduced from Protection Experiments with Purified Butyrylcholinesterase Butyrylcholinesterase in Human Tissues Summary: Functions of Butyrylcholinesterase Structure of Human Butyrylcholinesterase Conclusions and Future Directions Acknowledgments References
Key concepts: Butyrylcholinesterase, Acetylcholinesterase, Cholinesterase, Function (biology), Chemistry, Enzyme, Aché, Biochemistry