2011•Infection Control and Hospital EpidemiologyRequires access

Blood Concentrations of Chlorhexidine in Hospitalized Children Undergoing Daily Chlorhexidine Bathing

Andrew H. Lee, Robert Harlan, Autumn R. Breaud, Kathleen A. Speck, Trish M. Perl, William A. Clarke, Aaron Michael Milstone

Open publisher page 24 citations

Abstract

We collected serial blood samples from children in the intensive care unit who underwent daily bathing with 2% chlorhexidine gluconate (CHG)-impregnated cloths. Low concentrations of CHG were detected in a few blood samples, indicating absorption through intact skin. There was no suggestion that CHG accumulated in the blood with repeated exposures.

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What this paper is about

We collected serial blood samples from children in the intensive care unit who underwent daily bathing with 2% chlorhexidine gluconate (CHG)-impregnated cloths. Low concentrations of CHG were detected in a few blood samples, indicating absorption through intact skin. There was no suggestion that CHG accumulated in the blood with repeated exposures.

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OpenAlex reports 24 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

We collected serial blood samples from children in the intensive care unit who underwent daily bathing with 2% chlorhexidine gluconate (CHG)-impregnated cloths. Low concentrations of CHG were detected in a few blood samples, indicating absorption through intact skin. There was no suggestion that CHG accumulated in the blood with repeated exposures.

Key concepts: Bathing, Chlorhexidine, Chlorhexidine gluconate, Medicine, Intensive care unit, Antiseptic, Dentistry, Anesthesia

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