Blood Concentrations of Chlorhexidine in Hospitalized Children Undergoing Daily Chlorhexidine Bathing
Andrew H. Lee, Robert Harlan, Autumn R. Breaud, Kathleen A. Speck, Trish M. Perl, William A. Clarke, Aaron Michael Milstone
Abstract
Andrew H. Lee, Robert Harlan, Autumn R. Breaud, Kathleen A. Speck, Trish M. Perl, William A. Clarke, Aaron Michael Milstone
Abstract
We collected serial blood samples from children in the intensive care unit who underwent daily bathing with 2% chlorhexidine gluconate (CHG)-impregnated cloths. Low concentrations of CHG were detected in a few blood samples, indicating absorption through intact skin. There was no suggestion that CHG accumulated in the blood with repeated exposures.
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We collected serial blood samples from children in the intensive care unit who underwent daily bathing with 2% chlorhexidine gluconate (CHG)-impregnated cloths. Low concentrations of CHG were detected in a few blood samples, indicating absorption through intact skin. There was no suggestion that CHG accumulated in the blood with repeated exposures.
Key concepts: Bathing, Chlorhexidine, Chlorhexidine gluconate, Medicine, Intensive care unit, Antiseptic, Dentistry, Anesthesia