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2010•Clinical TransplantationOpen access

The impact of cytomegalovirus infection ≥1 year after primary renal transplantation

Barry J. Browne, Jo‐Anne H. Young, Ty B. Dunn, Arthur J. Matas

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Abstract

Browne BJ, Young J‐A, Dunn TB, Matas AJ. The impact of cytomegalovirus infection ≥1 yr after primary renal transplantation. Clin Transplant 2010: 24: 572–579. © 2010 John Wiley & Sons A/S. Abstract: We studied the impact of a first post‐transplant cytomegalovirus (CMV) infection greater than one year after primary kidney transplantation. Risk factors for developing late CMV were acute rejection and donor–recipient CMV status. Of those developing late CMV, 35% were donor (D) positive, recipient (R) negative; however, 23% were D+R+, 22% D−R+, and 15% D−R−. Late CMV was associated with significantly decreased patient and graft survival.

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What this paper is about

Browne BJ, Young J‐A, Dunn TB, Matas AJ. The impact of cytomegalovirus infection ≥1 yr after primary renal transplantation. Clin Transplant 2010: 24: 572–579. © 2010 John Wiley & Sons A/S. Abstract: We studied the impact of a first post‐transplant cytomegalovirus (CMV) infection greater than one year after primary kidney transplantation. Risk factors for developing late CMV were acute rejection and donor–recipient CMV status. Of those developing late CMV, 35% were donor (D) positive, recipient (R) negative; however, 23% were D+R+, 22% D−R+, and 15% D−R−. Late CMV was associated with significantly decreased patient and graft survival.

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Available abstract

Browne BJ, Young J‐A, Dunn TB, Matas AJ. The impact of cytomegalovirus infection ≥1 yr after primary renal transplantation. Clin Transplant 2010: 24: 572–579. © 2010 John Wiley & Sons A/S. Abstract: We studied the impact of a first post‐transplant cytomegalovirus (CMV) infection greater than one year after primary kidney transplantation. Risk factors for developing late CMV were acute rejection and donor–recipient CMV status. Of those developing late CMV, 35% were donor (D) positive, recipient (R) negative; however, 23% were D+R+, 22% D−R+, and 15% D−R−. Late CMV was associated with significantly decreased patient and graft survival.

Key concepts: Cytomegalovirus, Transplantation, Cytomegalovirus infection, Medicine, Cytomegalovirus infections, Kidney transplantation, Betaherpesvirinae, Renal transplant

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