Tramadol for control of shivering (Comparison with pethidine)
Aditi A Dhimar, Mamta G Patel, VN Swadia
Abstract
Aditi A Dhimar, Mamta G Patel, VN Swadia
Abstract
Shivering is common problem faced by an anaesthesiologist during intraoperative as well as in postoperative period. Shivering occurs during both general anaesthesia and regional anaesthesia, but it is more frequent and troublesome during regional anaesthesia. This randomized, prospective study conducted in 60 ASA grade I, II, or III patients, was designed to explore the efficacy and potency of Tramadol in comparison to Pethidine for control of shivering under regional anaesthesia. Patients received Tramadol or Pethidine in a dose of 1mg.kg -1 I.V after the appearance of shivering. Disappearance and recurrence of shivering, as well as haemodynamics were observed at scheduled intervals. Onset of disappearance of shivering was found at 1 minute in Tramadol group (T)( p < 0.05) and at 3 minutes in Pethidine group (P)( p < 0.05 ). The complete disappearance of shivering took 5 minutes in T group while 20 minutes in P group.Reccurence rate of shivering was 10% in T and 50% in P group patients respectively (p < 0.05). None of the patients had any complications except nausea and vomiting (6.6% and 20% in group T and P respectively, p> 0.05). Thus Tramadol and Pethidine were equally efficacious, but Tramadol was more potent with respect to control of shivering and its recurrence .It was concluded that I.V Tramadol is qualitatively superior to Pethidine for control of shivering.
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Shivering is common problem faced by an anaesthesiologist during intraoperative as well as in postoperative period. Shivering occurs during both general anaesthesia and regional anaesthesia, but it is more frequent and troublesome during regional anaesthesia. This randomized, prospective study conducted in 60 ASA grade I, II, or III patients, was designed to explore the efficacy and potency of Tramadol in comparison to Pethidine for control of shivering under regional anaesthesia. Patients received Tramadol or Pethidine in a dose of 1mg.kg -1 I.V after the appearance of shivering. Disappearance and recurrence of shivering, as well as haemodynamics were observed at scheduled intervals. Onset of disappearance of shivering was found at 1 minute in Tramadol group (T)( p < 0.05) and at 3 minutes in Pethidine group (P)( p < 0.05 ). The complete disappearance of shivering took 5 minutes in T group while 20 minutes in P group.Reccurence rate of shivering was 10% in T and 50% in P group patients respectively (p < 0.05). None of the patients had any complications except nausea and vomiting (6.6% and 20% in group T and P respectively, p> 0.05). Thus Tramadol and Pethidine were equally efficacious, but Tramadol was more potent with respect to control of shivering and its recurrence .It was concluded that I.V Tramadol is qualitatively superior to Pethidine for control of shivering.
Key concepts: Pethidine, Tramadol, Shivering, Anesthesia, Medicine, Analgesic