Pancreatic enzymes replacement therapy in chronic pancreatitis: an update.
Anca Trifan, Gheorghe G. Bălan, C Stanciu
Abstract
Anca Trifan, Gheorghe G. Bălan, C Stanciu
Abstract
Chronic pancreatitis is the major cause of exocrine pancreatic insufficiency which should be compensated by pancreatic enzyme replacement therapy. There are now available a great number of pancreatic enzyme preparations, but encapsulated enteric-coated microspheres and minimicrospheres are considered the enzyme treatment of choice. However, full compensation of pancreatic exocrine insufficiency with enzyme replacement therapy cannot be obtained in all patients with chronic pancreatitis.
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Chronic pancreatitis is the major cause of exocrine pancreatic insufficiency which should be compensated by pancreatic enzyme replacement therapy. There are now available a great number of pancreatic enzyme preparations, but encapsulated enteric-coated microspheres and minimicrospheres are considered the enzyme treatment of choice. However, full compensation of pancreatic exocrine insufficiency with enzyme replacement therapy cannot be obtained in all patients with chronic pancreatitis.
Key concepts: Pancreatitis, Pancreatic enzymes, Exocrine pancreatic insufficiency, Enzyme replacement therapy, Medicine, Enzyme deficiency, Gastroenterology, Internal medicine