2012•Unpublished venueRequires access

The Discovery of Citalopram and Its Refinement to Escitalopram

Klaus Peter Bøgesø, Connie Sánchez

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Abstract

This chapter contains sections titled: List of Abbreviations Introduction Discovery of Talopram Discovery of Citalopram Synthesis and Production of Citalopram The Pharmacological Profile of Citalopram Clinical Efficacy of Citalopram Synthesis and Production of Escitalopram The Pharmacological Profile of the Citalopram Enantiomers R-Citalopram's Surprising Inhibition of Escitalopram Binding Site(s) for Escitalopram on the Serotonin Transporter Future Perspectives on the Molecular Basis for Escitalopram's Interaction with the SERT Clinical Efficacy of Escitalopram Conclusions References

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What this paper is about

This chapter contains sections titled: List of Abbreviations Introduction Discovery of Talopram Discovery of Citalopram Synthesis and Production of Citalopram The Pharmacological Profile of Citalopram Clinical Efficacy of Citalopram Synthesis and Production of Escitalopram The Pharmacological Profile of the Citalopram Enantiomers R-Citalopram's Surprising Inhibition of Escitalopram Binding Site(s) for Escitalopram on the Serotonin Transporter Future Perspectives on the Molecular Basis for Escitalopram's Interaction with the SERT Clinical Efficacy of Escitalopram Conclusions References

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Available abstract

This chapter contains sections titled: List of Abbreviations Introduction Discovery of Talopram Discovery of Citalopram Synthesis and Production of Citalopram The Pharmacological Profile of Citalopram Clinical Efficacy of Citalopram Synthesis and Production of Escitalopram The Pharmacological Profile of the Citalopram Enantiomers R-Citalopram's Surprising Inhibition of Escitalopram Binding Site(s) for Escitalopram on the Serotonin Transporter Future Perspectives on the Molecular Basis for Escitalopram's Interaction with the SERT Clinical Efficacy of Escitalopram Conclusions References

Key concepts: Escitalopram, Citalopram, Serotonin transporter, Pharmacology, Psychology, Antidepressant, Psychiatry, Medicine

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