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2004•Current Protocols in ToxicologyRequires access

Measurement of Thioredoxin and Thioredoxin Reductase

Elias S.J. Arnér, Arne Holmgren

Open publisher page 147 citations

Abstract

The thioredoxin system is ubiquitous, providing reducing equivalents to essential biosynthetic enzymes like ribonucleotide reductase. It is essential for cellular redox regulation, control of oxidative stress, and protection against oxidative damage. This unit includes protocols for measuring thioredoxin or thioredoxin reductase in biological preparations or as purified enzymes.

About this research paper

What this paper is about

The thioredoxin system is ubiquitous, providing reducing equivalents to essential biosynthetic enzymes like ribonucleotide reductase. It is essential for cellular redox regulation, control of oxidative stress, and protection against oxidative damage. This unit includes protocols for measuring thioredoxin or thioredoxin reductase in biological preparations or as purified enzymes.

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OpenAlex reports 147 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The thioredoxin system is ubiquitous, providing reducing equivalents to essential biosynthetic enzymes like ribonucleotide reductase. It is essential for cellular redox regulation, control of oxidative stress, and protection against oxidative damage. This unit includes protocols for measuring thioredoxin or thioredoxin reductase in biological preparations or as purified enzymes.

Key concepts: Thioredoxin, Thioredoxin reductase, Ferredoxin-thioredoxin reductase, Chemistry, Biochemistry, Enzyme

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