2010•Universidad de Córdoba Insitutional Repository (Universidad de Córdoba)Open access
A comparison of quantitative proteomics methodologies on a differential experiment on test samples
Joan Josep Bech‐Serra, Núria Colomé, Marta Monge-Azemar, Françesc Canals
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Abstract
of technologies aimed to the analysis of large number of proteins, representing ideally the entire proteome, in the same experiment. In its early stages , mass spectrometry-based proteomics was successfully used to the qualitative characterization of complex mixtures of proteins, leaving the quantitative aspects in a secondary role, essentially because of the lack of suitable technologies for quantitative analysis of such complex mixtures. However, in the last years, a wide number of strategies have been developed
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