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2014•Unpublished venueOpen access

Immunohistochemical Assessment of p53 Protein and its Correlation with Clinicopathological Characteristics in Breast Cancer Patients

Robab Sheikhpour, Nasrin Ghassemi, Parichehreh Yaghmaei, Javad Mohiti Ardekani

Open full text 10 citations

Abstract

tients. There was no significant correlation between p53 immunostaining with clinicopathological parameters like grade, stage, tumor size, age of menarche, histological type, family history, and age of first pregnancy, but there was significant correlation between p53 staining with age (p-value=0.000). Spearman’s rho was used for assessment of statistical depen-dence between age and p53 (Correlation Coefficient=0.417, p-value=0.002). Also, there was significant difference between

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tients. There was no significant correlation between p53 immunostaining with clinicopathological parameters like grade, stage, tumor size, age of menarche, histological type, family history, and age of first pregnancy, but there was significant correlation between p53 staining with age (p-value=0.000). Spearman’s rho was used for assessment of statistical depen-dence between age and p53 (Correlation Coefficient=0.417, p-value=0.002). Also, there was significant difference between

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Available abstract

tients. There was no significant correlation between p53 immunostaining with clinicopathological parameters like grade, stage, tumor size, age of menarche, histological type, family history, and age of first pregnancy, but there was significant correlation between p53 staining with age (p-value=0.000). Spearman’s rho was used for assessment of statistical depen-dence between age and p53 (Correlation Coefficient=0.417, p-value=0.002). Also, there was significant difference between

Key concepts: Immunohistochemistry, Breast cancer, Immunostaining, Medicine, Pathological, P53 protein, Cancer, Pathology

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