Plasma cell dyscrasia; LCDD vs Immunotactoid glomerulopathy.
Wael Latif Jabur, Hareth M Saeed, Khalid A. Abdulla
Abstract
Wael Latif Jabur, Hareth M Saeed, Khalid A. Abdulla
Abstract
Light chain deposit disease is a plasma cell disorder characterized by production of a large amount of monoclonal immunoglobulin light chain or part of it, which is usually deposited as an amorphous substance in the kidneys. Immunotactoid glomerulopathy is an uncommon disease, which might be related to plasma cell dyscrasia, and characteristically manifest as organized glomerular ultra structural fibrils or microtubules. In this article, we report a case of a combined presentation of light chain disease and immunotactoid glomerulopathy in a patient with multiple myeloma and reversible advanced renal failure.
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Light chain deposit disease is a plasma cell disorder characterized by production of a large amount of monoclonal immunoglobulin light chain or part of it, which is usually deposited as an amorphous substance in the kidneys. Immunotactoid glomerulopathy is an uncommon disease, which might be related to plasma cell dyscrasia, and characteristically manifest as organized glomerular ultra structural fibrils or microtubules. In this article, we report a case of a combined presentation of light chain disease and immunotactoid glomerulopathy in a patient with multiple myeloma and reversible advanced renal failure.
Key concepts: Plasma cell dyscrasia, Dyscrasia, Medicine, Immunoglobulin light chain, Glomerulopathy, Paraproteinemias, Plasma cell, Pathology