2006•Encyclopedia of Life SciencesRequires access
Apoptosis: Regulatory Genes and Disease
Leonhard Müllauer, Sabine Wohlfart, Brigitte Scheucher
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Abstract
Abstract Apoptosis is a form of active cell death that proceeds along genetically determined and interacting pathways of biochemical reactions. It is essential for development and continuous physiological cell renewal in multicellular organisms. A deregulation of apoptosis contributes to the pathogenesis of various human diseases such as cancer, autoimmune disorders and neurodegenerative pathologies.