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2011•PubMedOpen access

Cyclosporine in the treatment of a case of fulminant and refractory acute disseminated encephalomyelitis.

Mohammd-Mehdi Taghdiri, Ali Amanati, Babak Abdolkarimi

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Abstract

BACKGROUND: Acute disseminated encephalomyelitis (ADEM) is a rare, monophasic, demyelinating disease of the CNS which sometimes could be refractory to traditional treatment. CASE PRESENTATION: We present a case of fulminant ADEM which is treated with combination of corticosteroid, intravenous immunoglobulin and cyclosporine. CONCLUSION: Immunosuppressive agents such as cyclosporine may be effective especially in fulminant form of the disease.

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BACKGROUND: Acute disseminated encephalomyelitis (ADEM) is a rare, monophasic, demyelinating disease of the CNS which sometimes could be refractory to traditional treatment. CASE PRESENTATION: We present a case of fulminant ADEM which is treated with combination of corticosteroid, intravenous immunoglobulin and cyclosporine. CONCLUSION: Immunosuppressive agents such as cyclosporine may be effective especially in fulminant form of the disease.

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Available abstract

BACKGROUND: Acute disseminated encephalomyelitis (ADEM) is a rare, monophasic, demyelinating disease of the CNS which sometimes could be refractory to traditional treatment. CASE PRESENTATION: We present a case of fulminant ADEM which is treated with combination of corticosteroid, intravenous immunoglobulin and cyclosporine. CONCLUSION: Immunosuppressive agents such as cyclosporine may be effective especially in fulminant form of the disease.

Key concepts: Fulminant, Acute disseminated encephalomyelitis, Medicine, Refractory (planetary science), Demyelinating disease, Disease, Immunology, Internal medicine

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Cyclosporine in the treatment of a case of fulminant and refractory acute disseminated encephalomyelitis. — Research Paper | ScholarLens