1990PubMedOpen access

[Tumor of the carotid body (paraganglioma)].

J Franklin, Saulo Romero Félix Gonçalves, E C Cruz

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Abstract

Carotid body tumours (paragangliomas) are uncommon but rather an interesting pathology, due to the controversy that still remains regarding their histopathologic behaviour (malignancy?), as well as their diagnosis and management. Because of its nature being composed of chemoreceptor paraganglionic tissue, the carotid body responds to lower partial pressure of oxygen and can cause severe cardiovascular disturbances. Based upon a series of 12 cases, the authors reviewed this pathology in detail, and discussed the methods of diagnosis and treatment, which they considered more appropriate.

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What this paper is about

Carotid body tumours (paragangliomas) are uncommon but rather an interesting pathology, due to the controversy that still remains regarding their histopathologic behaviour (malignancy?), as well as their diagnosis and management. Because of its nature being composed of chemoreceptor paraganglionic tissue, the carotid body responds to lower partial pressure of oxygen and can cause severe cardiovascular disturbances. Based upon a series of 12 cases, the authors reviewed this pathology in detail, and discussed the methods of diagnosis and treatment, which they considered more appropriate.

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Available abstract

Carotid body tumours (paragangliomas) are uncommon but rather an interesting pathology, due to the controversy that still remains regarding their histopathologic behaviour (malignancy?), as well as their diagnosis and management. Because of its nature being composed of chemoreceptor paraganglionic tissue, the carotid body responds to lower partial pressure of oxygen and can cause severe cardiovascular disturbances. Based upon a series of 12 cases, the authors reviewed this pathology in detail, and discussed the methods of diagnosis and treatment, which they considered more appropriate.

Key concepts: Carotid body, Paraganglioma, Malignancy, Medicine, Chemodectoma, Carotid bifurcation, Pathology, Chemoreceptor

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