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Immunomodulation induced by psoralen plus ultraviolet A radiation.

F. Aubin, P Humbert

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Abstract

Since 1974, psoralen plus ultraviolet A radiation (PUVA) has been widely used for the treatment of a variety of skin diseases. Because the pathology of diseases such as psoriasis, vitiligo, alopecia, lichen planus, atopic dermatitis, and graft-versus-host disease is thought to involve immune mechanisms, it has been suggested that at least some of the beneficial effects of PUVA may be due to its immunomodulatory properties. This paper [...]

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What this paper is about

Since 1974, psoralen plus ultraviolet A radiation (PUVA) has been widely used for the treatment of a variety of skin diseases. Because the pathology of diseases such as psoriasis, vitiligo, alopecia, lichen planus, atopic dermatitis, and graft-versus-host disease is thought to involve immune mechanisms, it has been suggested that at least some of the beneficial effects of PUVA may be due to its immunomodulatory properties. This paper [...]

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OpenAlex reports 9 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Since 1974, psoralen plus ultraviolet A radiation (PUVA) has been widely used for the treatment of a variety of skin diseases. Because the pathology of diseases such as psoriasis, vitiligo, alopecia, lichen planus, atopic dermatitis, and graft-versus-host disease is thought to involve immune mechanisms, it has been suggested that at least some of the beneficial effects of PUVA may be due to its immunomodulatory properties. This paper [...]

Key concepts: Psoralen, Vitiligo, Psoriasis, Medicine, Dermatology, Atopic dermatitis, PUVA therapy, Ultraviolet radiation

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