SLOW‐RELEASE ARTIFICIAL TEARS (SRAT) IN DRY EYE DISEASE

Twelve patients with keratoconjunctivitis sicca were treated with soluble inserts of a dehydrated cellulose polymer placed in the inferior conjunctival fornix. Compared with their previous use of liquid tear substitutes burning, photophobia and foreign body sensation were reduced in 7 patients. An increased tear film break up time (BUT) (P < 0.002) and a decreased rose bengal staining of cornea and conjunctiva (P <0.002) were recorded. The mean visual acuity did not change. Simultaneous use of 0.9% NaCl eye drops was necessary for comfort. The main disadvantage of the inserts was their tendency to dislocate. The hydroxy propyl cellulose inserts were supplied in an individual foil pack (Merck Sharp & Dohme‐Chibret Laboratories).