2010•European Journal of NeurologyOpen access

Diagnosing narcolepsy with cataplexy on history alone: challenging the International Classification of Sleep Disorders (ICSD-2) criteria

Ian A. Morrison, Jitka Bušková, Soňa Nevšímalová, Neil J Douglas, Renata L. Riha

Abstract

BACKGROUND AND PURPOSE: The second version of the International Classification of Sleep Disorders suggests narcolepsy with cataplexy can be diagnosed on history alone. PATIENTS: Five patients with a history supportive of narcolepsy/cataplexy. METHOD: Case review following clinical investigation. RESULTS: None of the five patients had a diagnosis of narcolepsy/cataplexy on the basis of objective testing using polysomnography (PSG) and multiple sleep latency testing (MSLT). CONCLUSION: PSG and MSLT should always be used in conjunction with a comprehensive history taken by an experienced sleep physician to support a diagnosis of narcolepsy with cataplexy and to exclude other conditions that may mimic narcolepsy.

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Key concepts: Narcolepsy, Cataplexy, Polysomnography, Multiple Sleep Latency Test, Medicine, Sleep disorder, Pediatrics, Sleep paralysis