Nathan Hitzeman, Flora Rafii
Abstract
Dopamine agonists, such as pramipexole (Mirapex), ropinirole (Requip), pergolide (formerly Permax), and apomorphine (Apokyn), improve the motor fluctuations and dyskinesias that commonly occur with levodopa, but at the expense of increasing nonmotor adverse effects and noncompliance. An individual, case-based approach should be employed.
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Dopamine agonists, such as pramipexole (Mirapex), ropinirole (Requip), pergolide (formerly Permax), and apomorphine (Apokyn), improve the motor fluctuations and dyskinesias that commonly occur with levodopa, but at the expense of increasing nonmotor adverse effects and noncompliance. An individual, case-based approach should be employed.
Key concepts: Pergolide, Pramipexole, Ropinirole, Medicine, Levodopa, Apomorphine, Parkinson's disease, Dopamine