2009•Kazan medical journalRequires access
Ранние маркеры дисфункции эндотелия в динамике развития артериальной гипертонии у лиц молодого возраста
Маянская Светлана Дмитриевна, Антонов Александр Рудольфович, Попова Анна Александровна, Гребенкина Ирина Аркадьевна
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Abstract
In 142 male patients with stage I hypertension found were disorders of endothelium-dependent vasodilation when performing a reactive hyperemia test and reduction of the growth of the diameter of the brachial artery in comparison with those in the control group. It was found that the disorder of the endothelium-dependent vasodilation was accompanied by a reduction in the endothelial production of nitric oxide, while the intensity of the endothelial dysfunction was closely correlated with indicators of an imbalance between proand antioxidant activity of blood, and the activity of the renin-angiotensin system.