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The effects of external CO2 application on human skin microcirculation investigated by laser Doppler flowmetry.

W. Schnizer, R. Erdl, Peter Schöps, N. Seichert

Abstract

The effects of an aqueous solution of CO2 applied to a small skin site were investigated by means of a laser Doppler flowmeter. The circulatory response to CO2 was an increased blood flow, reaching a maximum level within approximately 2-3 minutes. In addition there was a marked stimulation of rhythmical vasomotion, especially an increase in amplitudes. The effects, strongly dependent on dose and temperature, ceased rapidly when the CO2 sample was withdrawn.

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Available abstract

Key concepts: Vasomotion, Laser Doppler velocimetry, Microcirculation, Blood flow, Biomedical engineering, Circulatory system, Stimulation, Human skin